Dynein beta chain ciliary-like

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August undefined, 2024

WebDec 15, 2024 · For the upregulated miRNAs, the target DEGs of miR-1992-y present in the network were aarF domain-containing protein kinase 5-like isoform X1 (ADCK5), LRP2-binding protein-like (lrp2bp), dynein beta chain, ciliary-like isoform X8 (DNAH9), and axonemal dynein light chain domain-containing protein 1-like isoform X2 (AXDND1), … WebAug 26, 2024 · Dynein-2 cryo-EM structure determination. We purified the human dynein-2 complex by co-expressing all of its subunits from a single baculovirus in insect cells (Supplementary Fig. 1a–d) and ...

Dynein - Wikipedia

WebMar 20, 2024 · In axonemal dynein, the outer-arm dynein (OAD) complex, which comprises three heavy chains (α, β, and γ), produces the main driving force for ciliary/flagellar motility. It has recently been shown that axonemal dynein light chain-1 (LC1) binds to the microtubule-binding domain (MTBD) of OADγ, leading to a decrease in its microtubule … WebThe different dynein complexes hydrolyze MgATP at different rates, for example, the microtubule stimulated ATPase activity of bovine brain cytoplasmic dynein is 0.3 mol min −1 mg −1 and the activity of axonemal outer arm dynein is 2.0 mol min −1 mg −1.Different dynein complexes also move along microtubules at different rates. sharetheinfo

The complex of outer-arm dynein light chain-1 and the microtubu…

WebDynein was first discovered in the ciliary axoneme, where it causes the directed sliding between outer doublet microtubules that underlies ciliary bending. The initiation and propagation of ciliary bends are produced by a precisely located array of different dyneins containing eight or more different dynein heavy chain isoforms. WebPrimary ciliary dyskinesia. At least 21 mutations in the DNAI1 gene have been found to cause primary ciliary dyskinesia, which is a condition characterized by respiratory tract infections, abnormal organ placement, and an inability to have children (infertility).DNAI1 gene mutations result in an absent or abnormal intermediate chain 1. Without a normal … WebProtein. Dynein intermediate chain 2, ciliary. Status. UniProtKB reviewed (Swiss-Prot) Organism. Heliocidaris crassispina (Sea urchin) (Anthocidaris crassispina) Amino acids. 702. Protein existence. share the gospel verse

The dynein heavy chain: structure, mechanics and evolution

Dynein-2 intermediate chains play crucial but distinct roles in primary cil…

WebAug 8, 2024 · Dynein-2, also known as intraflagellar transport dynein, moves cargoes along the axoneme of eukaryotic cilia and flagella. Both dyneins operate as large ATP-driven … share the heartWebThe DNAH5 gene provides instructions for making a protein that is part of a group (complex) of proteins called dynein. This complex functions within cell structures called cilia. Cilia … poplar grove baptist church elizabethton tn

"WebMar 29, 2024 · Three transcripts were down-regulated in uninfected sunflower bees, one of which was characterized: dynein beta chain, ciliary-like (XP_033357315). Based on machine learning, we were able to correctly classify uninfected sunflower-fed from wildflower-fed bumble bees in 100% of the instances with the top 141 through 114 … " - Dynein beta chain ciliary-like

Dynein beta chain ciliary-like

The complex of outer-arm dynein light chain-1 and the …

Web1 day ago · Outer dynein arms in the ciliary axoneme generate force for ciliary beating. Here, cryo-electron tomography study of the outer dynein arm from the unicellular alga … WebMar 20, 2024 · Axonemal dynein is a microtubule-based molecular motor that drives ciliary/flagellar beating in eukaryotes. In axonemal dynein, the outer-arm dynein (OAD) …

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WebGene ID: 104958303, updated on 2-Sep-2024. Summary Other designations. dynein beta chain, ciliary-like WebDynein-1 is responsible nearly all minus-end directed intracellular transport and has essential roles in cell division. • Dynein-2 drives intraflagellar transport in cilia. • …

WebSep 30, 2024 · 63 in the nexin-dynein regulatory complex, in the radial spokes, and associated with the central pair of 64 microtubules, for example. 65 Here, we identify a Tctex-type dynein light chain in T. brucei that we named TbLC2 because it has 66 sequence homology, structural similarity, and ciliary localization like LC2 homologs in … WebDec 8, 2024 · Summary. DNAH7 is a component of the inner dynein arm of ciliary axonemes (Zhang et al., 2002 [PubMed 11877439]). [supplied by OMIM, Mar 2008] Expression. …

WebMay 1, 2001 · The dynein heavy chain family of isoforms is divided into four functional classes: (i) axonemal (ciliary or flagellar) outer arm dyneins; (ii) axonemal inner arm … WebSep 30, 2024 · 37 of dynein motor proteins coordinate their activity to drive ciliary bending wave propagation. Dynein-38 associated light and intermediate chains regulate the …

WebGene ID: 105007220, updated on 28-Jan-2024. Summary Other designations. dynein heavy chain 11, axonemal, dynein beta chain, ciliary, dynein beta chain, ciliary

WebThe genes encoding two Paramecium dynein heavy chains, DHC-6 and DHC-8, have been cloned and sequenced. Sequence-specific antibodies demonstrate that DHC-6 encodes ciliary outer arm beta-chain and DHC-8 encodes a cytoplasmic dynein heavy chain. Therefore, this study is the first opportunity to compa … poplar grove body shopWebSep 26, 2024 · In summary, we identified TbLC2 as a ciliary dynein light chain of the Tctex1/Tctex2 family that is necessary for various aspects of ciliary motility in trypanosome cells. Our work demonstrates that TbLC2 … poplar grove baptist church gaithersburg mdWebAs an important first step, the three heavy chains of the ciliary outer arm dynein of paramecium were characterized. Sucrose density gradient centrifugation in a high salt buffer separated the dynein into a 22S species, which contained the alpha and beta heavy chains, and a 12S species, which contained the gamma chain as well as the inner arm ... poplar grove body shop gainesboro tnWebSep 26, 2024 · For example, LC4, a calmodulin-like outer arm dynein light chain also known as DLE1 , induces a Ca 2+ dependent conformational change in the N-terminal tail domain of the γ HC (DHC15 ) that activates the motor in Chlamydomonas reinhardtii cells (a single-celled alga that is commonly used as a model organism for ciliary motility) . poplar grove baptist church trenton tnWebMay 1, 2001 · The dynein heavy chain family of isoforms is divided into four functional classes: (i) axonemal (ciliary or flagellar) outer arm dyneins; (ii) axonemal inner arm dyneins; (iii) non-axonemal (‘cytoplasmic’) dynein-1, also called MAP1C, Dhc1a and Dyh1; and (iv) cytoplasmic dynein-2, also called Dhc1b and Dyh2 ... the C. elegans genome ... share the harvest food pantry greenview moWebAn autosomal recessive disorder characterized by the association of primary ciliary dyskinesia with situs inversus. Clinical features include recurrent respiratory infections, bronchiectasis, infertility, and lateral transposition of the viscera of the thorax and abdomen. The situs inversus is most often total, although it can be partial in ... share the hope rochesterWebThe different dynein complexes hydrolyze MgATP at different rates, for example, the microtubule stimulated ATPase activity of bovine brain cytoplasmic dynein is 0.3 mol … share the hope