Cytohubba stress

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August undefined, 2024

WebApr 1, 2024 · The extent of drought stress is varieties and time-dependent, however, the molecular response mechanisms of drought tolerance in sunflower with different varieties are still unclear. ... CytoHubba analysis showed that the top 10 genes all encoded ribosomal proteins. Up-regulated genes were enriched in the KEGG pathway of … WebFinally, the hub genes were screened from the PPI network using the MCC algorithm of CytoHubba plugin. ... Functional enrichment analysis indicated that DEGs were mainly …

Transcriptomic analysis of Simpson Golabi Behmel syndrome

WebMar 15, 2024 · CytoHubba, which has been widely used to explore important nodes in biological networks, was then applied to identify the lip and oral cavity carcinoma hub proteins in the PPI network. ... The PI3K/Akt pathway is a central controller of viability in response to cell stress (e.g., pH, nutrient, and oxygen levels), and deregulation of the … WebNational Center for Biotechnology Information download images from icloud to iphone

cytoHubba: Identifying hub objects and sub-networks from …

WebApr 11, 2024 · In addition, the MCC module in the Cytohubba plugin filtered the top 20 hub genes in each of the three datasets and then took the intersection of the top 20 hub genes to determine the common hub genes by Venn software, ... (ASK1) by histone modifications in sufficient cells induces oxidative stress to reduce glomerular injury. Bioinformatics ... WebIn the comparisons, 932 and 384 overlapping transcripts were consistently up- and down-regulated, respectively. Combining the results of protein-protein interaction network analysis MCODE and CytoHubba, 55 up-regulated hub genes from four clusters and 9 down-regulated genes were identified. WebJan 4, 2024 · The Cytoscape plugin cytoHubba was applied to identify hub genes from the PPI network. Connectivity value and stress methods were used to identify hub genes. Significant clusters were generated by using PEWCC (version 1.0) . Significant transcription factors (TFs) were screened by generating the TF-gene network. download images from link online

The microRNA Cargo of Human Vaginal Extracellular Vesicles ...

Identification of Hub Genes in Patients with Alzheimer Disease and ...

WebThe target genes in the PPI network were identified with the cytoHubba plugin of Cytoscape. Here, the common algorithms (MCC, MNC, EPC, Degree, Closeness, Stress, and Radiality) were used to ... WebAug 6, 2024 · Lu et al. used CytoHubba MCC method in their study to screen out hub genes, whereas Huang et al. identified serpin family E member 1 (SERPINE1) as a novel biomarker for diffuse lower-grade gliomas via CytoHubba stress algorithm and CytoHubba betweenness algorithm (49, 50). Considering that all these algorithms were effective … download images from getty without watermarkWebCytoHubba provides 11 topological analysis methods including Degree, Edge Percolated Component, Maximum Neighborhood Component, Density of Maximum Neighborhood Component, Maximal Clique Centrality and six centralities (Bottleneck, EcCentricity, Closeness, Radiality, Betweenness, and Stress) based on shortest paths. download images from links

"WebJul 30, 2024 · Stress is a state of the body a non-specific response to any demand for change. Cancer had a deep relation with stress. Activation of the stress response and … " - Cytohubba stress

Cytohubba stress

Frontiers Identification of oxidative stress-related genes and ...

WebJul 30, 2024 · Stress is a state of the body a non-specific response to any demand for change. Cancer had a deep relation with stress. Activation of the stress response and exposure to the associated hormones could promote the growth and spread of tumors. The immune system can be important for finding and eliminating cancer cells. WebDownload scientific diagram Top 10 hub genes ranked by MCC method in cytoHubba. from publication: Prediction of Mechanosensitive Genes in Vascular Endothelial Cells …

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WebDec 7, 2024 · STRING, Cytoscape, MCODE and Cytohubba were used to construct a protein-protein interaction (PPI) network and screen key EP-DEGs. Key EP-DEGs levels … WebMar 17, 2024 · Combining multiple ML and cytohubba algorithms yielded 11 relevant genes. ... (Figure 5), in order to further screen for key hub genes, the Stress, MCC, Degree, EPC, EcCentricity, Radiality, Closeness and Betweenness algorithms were used to calculate the associated gene scores (Supplementary Figure S2A–G).

WebMar 18, 2024 · The top 20 hub genes were calculated using the seven algorithms of the plug-in CytoHubba ... Closeness, Radiality, Stress, and EPC) were used in evaluating and selecting hub genes. WebFeb 22, 2024 · We used algorithms of Cytohubba, molecular complex detection, Lasso logistic regression, and support vector machine to identify the key biomarkers. ... Cardiac myocytes have elevated levels of THBS1 in response to stress stimulation 15 and THBS1 can release active TGF-β and trigger fibrosis. 16 This trial demonstrates that THBS1 is …

WebThe CYBA gene provides instructions for making a protein called the cytochrome b-245 alpha chain (also known as p22-phox). This protein is one part (subunit) of a group of … WebThe data set obtained from string analysis is imported into Cytoscape, and Cytohubba, a plug-in of Cytoscape, 16 is used to select the central gene of biological network. In this study, the first 15 genes were selected as the central genes. ... Stress methods in cytoHubba. Construction and Analysis of the Key Gene Co-Expression Network.

WebNov 26, 2024 · The key genes were output by the four algorithms' maximum neighborhood component (MNC), degree, maximal clique centrality (MCC), and stress in cytoHubba …

WebAug 8, 2024 · Twelve methods in cytoHubba (Betweenness, BottleNeck, Closeness, Clustering Coefficient, Degree, DMNC, EcCentricity, EPC, MCC, MNC, Radiality, and Stress) were used to rank and evaluate the hub genes, and to finally generate the hub gene network; DAVID was used for hub gene enrichment analysis of GO, and KEGG further … class 6 hazWebJan 4, 2024 · We identified 17 hub genes that were closely associated with oxidative stress in AS and constructed a four-gene (aldehyde dehydrogenase six family member A1 ( ALDH6A1 ), eukaryotic elongation factor 2 kinase ( EEF2K ), glutaredoxin ( GLRX) and l -lactate dehydrogenase B ( LDHB )) diagnostic model with good accuracy. class 6 gvwWebExplore important nodes/hubs and fragile motifs in an interactome network by several topological algorithms including Degree, Edge Percolated Component (EPC), Maximum … download images from istockphoto freeWebNov 26, 2024 · The target of RA was screened based on Comparative Toxicogenomics Database (CTD). The key genes were output by the four algorithms' maximum neighborhood component (MNC), degree, maximal clique centrality (MCC), and stress in cytoHubba in Cytoscape, while biological functions and pathways were also analyzed. class 6 gsa approved safeWebfrom publication: cytoHubba: Identifying hub objects and sub-networks from complex interactome Background Network is a useful way for presenting many types of biological data including protein ... download images from icloud to pcWebApr 30, 2024 · HCC is hard to diagnose and has a poor prognosis due to the less understanding of the molecular pathological mechanisms and the regulation … download images from redditWebcytoHubba. Predicts and explores important nodes and subnetworks in a given network by several topological algorithms. Categories: clustering, Connection sub-graph discovery, graph analysis, network … class 6 hindi bal ram katha